We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A clinical score predicting a brief and uneventful course of newly diagnosed idiopathic trombocytopenic purpura in children.
- Authors
Edslev, Pernille Wendtland; Rosthøj, Steen; Treutiger, Iris; Rajantie, Jukka; Zeller, Bernward; Jonsson, Olafur G.
- Abstract
The Nordic idiopathic thrombocytopenic purpura study data showed that morbidity occurred mainly in children with thrombocytopenia lasting >3 months, whereas, the risk period with platelet counts <20 × 109/l was short and the number of bleeding events low in children with shorter disease duration. These brief, uneventful courses were predicted by developing a scoring system based on six clinical features: abrupt onset (weight 5), age <10 years (3), preceding infection (2), platelet count <5 × 109/l, wet purpura (1) and male gender (1). The score was derived and validated in two different cohorts of children. High scores (10–14) clearly identified low-risk patients. The score provides valid prognostic information and may be useful in clinical decision-making.
- Subjects
THROMBOCYTOPENIA; BLOOD platelet disorders; HEMORRHAGE; KAPOSI'S sarcoma; PURPURA (Pathology); THROMBOPENIC purpura
- Publication
British Journal of Haematology, 2007, Vol 138, Issue 4, p513
- ISSN
0007-1048
- Publication type
Article
- DOI
10.1111/j.1365-2141.2007.06682.x