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- Title
Erythrocyte deformability evaluated by laser diffractometry in polycythemia vera.
- Authors
Presti, Rosalia Lo; Caracciolo, Clementina; Montana, Maria; Barone, Rita; Catania, Anna; Caimi, Gregorio
- Abstract
We evaluated the erythrocyte deformability in a group of subjects with polycythemia vera (PV) using a Rheodyn-SSD Laser Diffractometer, at the shear stresses of 6, 12, 30 and 60 Pa. Our data showed a significant decrease of red cell deformability, expressed as elongation index (EI), in PV subjects compared with normal controls. These results suggest that the hyperviscosity syndrome accompanying this myeloproliferative disease may be considered a mixed form, resulting from the association of a polycythemic condition with a sclerocythemic disorder.
- Subjects
ERYTHROCYTE disorders; DIFFRACTOMETERS; LASERS; POLYCYTHEMIA vera; BLOOD diseases; BLOOD hyperviscosity syndrome
- Publication
Clinical Hemorheology & Microcirculation, 2012, Vol 50, Issue 3, p189
- ISSN
1386-0291
- Publication type
Article
- DOI
10.3233/ch-2010-1422