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- Title
State of the Art: Newer biomarkers in heart failure.
- Authors
de Boer, Rudolf A.; Daniels, Lori B.; Maisel, Alan S.; Januzzi, James L.
- Abstract
Since natriuretic peptides were successfully integrated into the clinical practice of heart failure ( HF), the possibility of using new biomarkers to advance the management of affected patients has been explored. While a huge number of candidate HF biomarkers have been described recently, very few have made the difficult translation from initial promise to clinical application. These markers mirror the complex pathophysiology of heart failure at various levels: cell loss (troponin), fibrosis ( ST2 and galectin-3), infection (procalcitonin), and renal disease (several renal markers). In this review, we examine the best emerging candidates for clinical assessment and management of patients with HF.
- Subjects
BIOMARKERS; HEART failure; HEART failure patients; HEART failure treatment; NATRIURETIC peptides; DIAGNOSIS
- Publication
European Journal of Heart Failure, 2015, Vol 17, Issue 6, p559
- ISSN
1388-9842
- Publication type
Article
- DOI
10.1002/ejhf.273