We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Diyabetik Ayak Sendromu ve Tip 2 Diabetes Mellitus'da İnflamasyonun Bir Göstergesi Olarak İnterlökinler.
- Authors
KALELİ, Süleyman; VARIM, Ceyhun; NALBANT, Ahmet; YAZAR, Hayrullah; AKDOĞAN, Mehmet
- Abstract
Objective: Diabetic foot ulcers that are one of the factors determined the duration and quality of life of diabetic patients are one of the most frequent causes of hospitalization and surgery. In this study, it was aimed to investigate the levels of interleukin (IL) 12 P70, 17, 18, HbA1c, and some parameters in subjects with type 2 diabetic mellitus, diabetic foot syndromes. Methods: The study was performed on three groups. They were patients with diabetic foot, patients with diabetes mellitus type 2 and healthy individuals (control). IL-12 P70, IL-17, and IL-18, HbA1c levels and other biochemical tests were compared for the three groups. Results: We found higher IL-17, IL-18, WBC, glucose and HbA1c in the diabetic and diabetic foot groups than control group. IL-12 P70 levels in diabetic foot group were significantly higher compared to control group. The performances in diagnosing of IL-12 P70, 17 and 18 as a biomarker for diabetic foot were statistically significant. IL-12 P70, 17 and 18 levels in diabetic patients were not statically significant compared with diabetic foot patients. Conclusion: In this study, it is thought that IL-12 P70, IL-17 and IL-18 for diabetic foot can be used as biomarkers. Further studies are needed to show the role of IL-12 P70, IL-17 and IL-18 levels in chronic inflammatory diseases as a biomarker.
- Publication
Bezmialem Science, 2018, Vol 6, Issue 4, p1
- ISSN
2148-2373
- Publication type
Article
- DOI
10.14235/bs.2018.2077