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- Title
A critical reflection on the grading of the certainty of evidence in umbrella reviews.
- Authors
Schlesinger, Sabrina; Schwingshackl, Lukas; Neuenschwander, Manuela; Barbaresko, Janett
- Abstract
A commentary by Stefania Papatheodorou provided an overview and guidance about umbrella reviews and why they are needed [[1]]. The GRADE (Grading of Recommendations, Assessment, Development and Evaluations) working group has developed a systematic, sensible and transparent approach to grade the certainty of evidence and its strength of recommendations, which are adopted from considerations arising from the Bradford Hill criteria for causation [[4]]. However, the reliance solely on "statistical significance" (expressed mainly as I p i -values) should not be the way forward, and further aspects such as the risk of bias need to be considered to judge the certainty of evidence.
- Subjects
CRITICAL thinking; CERTAINTY; UMBRELLAS; EVIDENCE; GLEASON grading system
- Publication
European Journal of Epidemiology, 2019, Vol 34, Issue 9, p889
- ISSN
0393-2990
- Publication type
Letter
- DOI
10.1007/s10654-019-00531-4