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- Title
Staphylococcus aureus mediastinitis following a skin infection in a non-immunocompromised patient: A case report.
- Authors
Mantzouranis, Konstantinos; Georgakopoulou, Vasiliki Epameinondas; Mermigkis, Dimitrios; Damaskos, Christos; Garmpis, Nikolaos; Papalexis, Petros; Gkoufa, Aikaterini; Drossos, Panagiotis; Chlapoutakis, Serafeim; Garmpi, Anna; Sklapani, Pagona; Trakas, Nikolaos; Tsiafaki, Xanthi
- Abstract
Mediastinitis is a severe inflammation of the structures located in the mid-chest cavity. Three main causes of infective mediastinitis are traditionally recognized: Deep infection of a sternal wound following cardiothoracic surgery, perforation of the esophagus, and the descending necrotizing mediastinitis as a result of odontogenic, pharyngeal or cervical infections. Mediastinitis, as a complication of skin infection with hematogenous spread is infrequent. Methicillin-resistant Staphylococcus aureus (MRSA) is a gram-positive bacteria, and is responsible for numerous severe infections. MRSA mediastinitis is a rare infection and is typically associated with complications of sternotomy and retropharyngeal abscesses. Here, the second known case of mediastinitis of a hematogenous origin in a non-immunocompromised 41-year-old patient following primary skin infection, accompanied by sternal osteomyelitis, lung consolidation and pleural effusion is described; MRSA was the responsible pathogen. The clinical course was favorable after 6 weeks of antibiotics administration without drainage or surgical intervention.
- Subjects
MEDIASTINITIS; SKIN infections; STAPHYLOCOCCUS aureus; METHICILLIN-resistant staphylococcus aureus; INFECTION; ESOPHAGEAL perforation
- Publication
Biomedical Reports, 2021, Vol 15, Issue 6, pN.PAG
- ISSN
2049-9434
- Publication type
Case Study
- DOI
10.3892/br.2021.1480