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Title
Optimization and scale-up using a micro reactor.
Abstract
The article reports that the Cambridge, England-based Uniqsis Ltd. has published an application note which describes an easy scale-up without re-optimization using a microreactor. The study used the FlowSyn continuous flow reactor equipped with exchangeable micro reactor technology to optimize nucleophilic aromatic substitution reaction. It is noted that the reaction was conducted at fixed pressure and flow-rate over a range of temperatures from 40-160 degrees Celsius.