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- Title
Mosquitocidal effect of ivermectin-treated nettings and sprayed walls on Anopheles gambiae s.s.
- Authors
Hamid-Adiamoh, Majidah; Muhammad, Abdul Khalie; Assogba, Benoit Sessinou; Soumare, Harouna Massire; Jadama, Lamin; Diallo, Moussa; D'Alessandro, Umberto; Ousmane Ndiath, Mamadou; Erhart, Annette; Amambua-Ngwa, Alfred
- Abstract
Ivermectin (IVM) has been proposed as a new tool for malaria control as it is toxic on vectors feeding on treated humans or cattle. Nevertheless, IVM may have a direct mosquitocidal effect when applied on bed nets or sprayed walls. The potential for IVM application as a new insecticide for long-lasting insecticidal nets (LLINs) and indoor residual spraying (IRS) was tested in this proof-of-concept study in a laboratory and semi-field environment. Laboratory-reared, insecticide-susceptible Kisumu Anopheles gambiae were exposed to IVM on impregnated netting materials and sprayed plastered- and mud walls using cone bioassays. The results showed a direct mosquitocidal effect of IVM on this mosquito strain as all mosquitoes died by 24 h after exposure to IVM. The effect was slower on the IVM-sprayed walls compared to the treated nettings. Further work to evaluate possibility of IVM as a new insecticide formulation in LLINs and IRS will be required.
- Subjects
ANOPHELES gambiae; INSECTICIDE-treated mosquito nets; INSECTICIDE application; AEDES aegypti; MALARIA prevention; MOSQUITOES
- Publication
Scientific Reports, 2024, Vol 14, Issue 1, p1
- ISSN
2045-2322
- Publication type
Article
- DOI
10.1038/s41598-024-63389-x