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- Title
What you need to know about migraine in Hughes syndrome patients.
- Authors
Schofield, JR; Hassell, KL
- Abstract
Background: Headache, often migrainous, is common in patients with antiphospholipid antibodies, whether or not they meet Sydney criteria for a definite diagnosis of Hughes syndrome. Migraine may be a harbinger of stroke in this patient population and even refractory migraine may be highly responsive to antithrombotic therapy in this clinical context. Purpose: To summarize what is known to date about managing this important manifestation of the immune-mediated hypercoagulable Hughes syndrome. Results: We provide a suggested management algorithm for refractory headache in this unique patient population. Conclusion: Most neurologists don't see or recognize many aPL-positive patients in their practice, so hematologists and rheumatologists who see these patients should recognize that refractory headache may be a manifestation of their immune-mediated hypercoagulable disorder and understand that the potential risks of not addressing this issue may be high.
- Subjects
MIGRAINE; PHOSPHOLIPID antibodies; FIBRINOLYTIC agents; THROMBOTIC thrombocytopenic purpura; STROKE patients; ANTIPHOSPHOLIPID syndrome; HEMATOLOGISTS
- Publication
Lupus, 2023, Vol 32, Issue 3, p319
- ISSN
0961-2033
- Publication type
Article
- DOI
10.1177/09612033231153790