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- Title
Diagnosis and Management of Insulinomas in a Tertiary Referral Center: A 10-Year Review.
- Authors
Ramachandran, V.; Shivashankara, V. Undemane; Rao, G.
- Abstract
Introduction: Insulinomas are rare tumors. There are few reports of insulinoma from India. We present a retrospective analysis of patients with insulinoma evaluated at a tertiary referral center in South India. Aim(s): To study the prevalence, clinical presentation, diagnostic techniques and surgical procedures employed in treating insulinomas. Materials and methods: Medical records of patients with insulinomas seen in the period 2000-2010 were retrieved from the hospital's medical records department and the records of the Departments of Gastro-intestinal Surgery, Radiology & Endocrinology. From these, data on clinical and diagnostic features, localization and surgical outcome were extracted. Preoperative localization of tumor was attempted using a combination of radiological techniques, including trans-abdominal US, conventional contrast-enhanced CT scan, dual-phase CECT, magnetic resonance imaging (MRI), conventional pancreatic arteriography and selective pancreatic arteriography, namely, intra-arterial digital subtraction angiography with or without CECT. Results: Thirty-one patients were diagnosed with Insulinoma. Dual Phase CECT Scan & IADSA had the highest sensitivity for preoperative localisation. IOUS was useful for intraoperative localisation. Most of pancreatic tumors were localised to the tail. Conclusion: Our experience shows that good results can be obtained in centers where facilities for Dual Phase CT Scan, IADSA & IOUS are available.
- Subjects
INSULINOMA; MEDICAL records; MEDICAL informatics; MAGNETIC resonance imaging; DIGITAL angiography
- Publication
Neuroendocrinology, 2012, Vol 96, p55
- ISSN
0028-3835
- Publication type
Article