We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Regulation of mitochondrial calcium in plants versus animals.
- Authors
Wagner, Stephan; De Bortoli, Sara; Schwarzländer, Markus; Szabò, Ildikò
- Abstract
Ca2+ acts as an important cellular second messenger in eukaryotes. In both plants and animals, a wide variety of environmental and developmental stimuli trigger Ca2+ transients of a specific signature that can modulate gene expression and metabolism. In animals, mitochondrial energy metabolism has long been considered a hotspot of Ca2+ regulation, with a range of pathophysiology linked to altered Ca2+ control. Recently, several molecular players involved in mitochondrial Ca2+ signalling have been identified, including those of the mitochondrial Ca2+ uniporter. Despite strong evidence for sophisticated Ca2+ regulation in plant mitochondria, the picture has remained much less clear. This is currently changing aided by live imaging and genetic approaches which allow dissection of subcellular Ca2+ dynamics and identification of the proteins involved. We provide an update on our current understanding in the regulation of mitochondrial Ca2+ and signalling by comparing work in plants and animals. The significance of mitochondrial Ca2+ control is discussed in the light of the specific metabolic and energetic needs of plant and animal cells.
- Subjects
CALCIUM; ENDOPHYTES; EUKARYOTES; BIOLOGICAL rhythms in animals; GENE expression
- Publication
Journal of Experimental Botany, 2016, Vol 67, Issue 13, p3809
- ISSN
0022-0957
- Publication type
Article
- DOI
10.1093/jxb/erw100