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- Title
DIFFUSE IDIOPATHIC SKELETAL HYPEROSTOSIS IN SUBJECTS WITH CONGESTIVE HEART FAILURE UNDERGOING CARDIAC REHABILITATION: A DECISION TREE ANALYSIS.
- Authors
AMBROSINO, Pasquale; SCRUTINIO, Domênico; DE CAMPI, Maurizio; MINIERO, Enzo; FORMISANO, Roberto; SPEDICATO, Giorgio Alfredo; IANNUZZI, Gian Luca; PAPPONE, Nicola
- Abstract
Objective: To assess the prevalence of diffuse idiopathic skeletal hyperostosis and its relationship with vascular risk factors among patients with congestive heart failure. Design: Population-based cross-sectional study. Participants: A total of 584 consecutive patients admitted to a Rehabilitative Cardiology Unit. Methods: Chi-square Automatic Interaction Detector (CHAID) decision tree analysis was used to build a predictive model. Results: The mean age (standard deviation) of the study population was 68.1 years (standard deviation 12.3), and 77.7% of the subjects were men. The overall prevalence of diffuse idiopathic skeletal hyperostosis in the cohort was 49.8%. Logistic regression analysis showed that age was a predictor of diffuse idiopathic skeletal hyperostosis (odds ratio 1.034; 95% confidence interval: 1.021-1.047, p< 0.001), with increasing odds ratios for increasing age tertiles. The CHAID prediction model identified 2 age "buckets": ≤ 69 and > 69 years. Patients > 69 years had a diffuse idiopathic skeletal hyperostosis prevalence of 60.1%, compared with 39.2% among those ≤ 69 years. Notably, body mass index was a predictor of diffuse idiopathic skeletal hyperostosis in this younger subset of patients (p = 0.028), with 2 body mass index buckets, ≤23.3 and > 23.3 kg/m², the latter showing more than twice the prevalence of diffuse idiopathic skeletal hyperostosis (43.2% vs 20%). Conclusion: Diffuse idiopathic skeletal hyperostosis is extremely frequent among patients with congestive heart failure, with age and body mass index being the strongest predictors.
- Subjects
ITALY; AGE distribution; CHI-squared test; CONFIDENCE intervals; DECISION trees; EPIDEMIOLOGICAL research; EXOSTOSIS; FORECASTING; CARDIAC rehabilitation; HEART failure; LONGITUDINAL method; MULTIVARIATE analysis; PROBABILITY theory; REGRESSION analysis; REHABILITATION centers; SPINAL osteophytosis; STATISTICAL hypothesis testing; T-test (Statistics); LOGISTIC regression analysis; BODY mass index; CROSS-sectional method; DATA analysis software; DESCRIPTIVE statistics; ODDS ratio
- Publication
Journal of Rehabilitation Medicine (Stiftelsen Rehabiliteringsinformation), 2020, Vol 52, Issue 3, p1
- ISSN
1650-1977
- Publication type
Article
- DOI
10.2340/16501977-2658