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- Title
Vitex doniana L. Growing in Southwestern Nigeria: Leaf Essential Oil Composition and Antimicrobial Activity.
- Authors
Owolabi, Moses S.; Ogundajo, Lanre Akintayo; Satyal, Prabodh; Dosoky, Noura S.; Abdulhakam, Wada; Olubukola, Davies-Sani Rayhana; Setzer, William N.
- Abstract
Introduction: Vitex doniana is used in traditional medicine for treatment of several ailments, including conjunctivitis, skin rashes due to measles or chickenpox, respiratory infections, and abdominal disorders and diarrhea. Methods: The leaf essential oil of V. doniana from southwestern Nigeria was obtained by hydrodistillation and analyzed by gas chromatography-mass spectrometry. The essential oil was screened for antimicrobial activity against a panel of pathogenic bacteria and fungi. Results: Major components in the essential oil were (E)-β-caryophyllene (12.34%), phytone (9.73%), phytol (16.87%), and incensyl acetate (23.57%). Conclusion: The essential oil showed notable antifungal activity against Aspergillus niger (MIC 78.1 μg/mL) and should be considered as an alternative or complementary option for antifungal therapy.
- Subjects
NIGERIA; ESSENTIAL oils; GAS chromatography/Mass spectrometry (GC-MS); VITEX; ANTI-infective agents; ASPERGILLUS niger
- Publication
Natural Product Communications, 2022, Vol 17, Issue 11, p1
- ISSN
1934-578X
- Publication type
Article
- DOI
10.1177/1934578X221141777