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- Title
Effectiveness of propagermanium treatment in multiple myeloma patients.
- Authors
Tsutsumi, Yutaka; Tanaka, Junji; Kanamori, Hiroe; Musashi, Mio; Minami, Hiina; Fukushima, Arata; Yamato, Hiroaki; Ehira, Nobuyuki; Kawamura, Takahito; Obara, Shinji; Ogura, Nobutaka; Asaka, Masahiro; Imamura, Masahiro; Masauzi, Nobuo
- Abstract
Tsutsumi Y, Tanaka J, Kanamori H, Musashi M, Minami H, Fukushima A, Yamato H, Ehira N, Kawamura T, Obara S, Ogura N, Asaka M, Imamura M, Masauzi N. Effectiveness of propagermanium treatment in multiple myeloma patients. Eur J Haematol 2004: 73: 397–401.© Blackwell Munksgaard 2004.Interferon (IFN) is one of several drugs effective in treating multiple myeloma (MM), and propagermanium is an IFN inducer. We report on 10 MM patients who were treated with propagermanium at doses from 10 to 40 mg. Two patients achieved complete remission (CR), two patients achieved partial remission (PR), and the condition of four patients was stable (stable disease, SD). After discontinuation of propagermanium, the status of MM progressed in two patients who were in SD and in two patients who had achieved PR. The administration of propagermanium was restarted in one patient resulting in a decrease in her paraprotein.
- Subjects
MULTIPLE myeloma; PLASMACYTOMA; ANTINEOPLASTIC agents; ANTIVIRAL agents; INTERFERONS; LYMPHOKINES
- Publication
European Journal of Haematology, 2004, Vol 73, Issue 6, p397
- ISSN
0902-4441
- Publication type
Article
- DOI
10.1111/j.1600-0609.2004.00330.x