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- Title
Results of balloon pulmonary valvoplasty in children with Noonan's syndrome.
- Authors
Holzmann, Jonathon; Rosenthal, Eric; Qureshi, Shakeel; Morgan, Gareth; Krasemann, Thomas; Tibby, Shane M.
- Abstract
Pulmonary valve stenosis is common in patients with Noonan's syndrome. The response to balloon valvoplasty varies.We assessed the correlation between re-intervention rate, immediate response, and the progress of the valve gradient over time after intervention.<bold>Methods: </bold>This is a retrospective study conducted from 1995 to 2014.<bold>Results: </bold>Of 14 patients identified, seven had re-intervention 28±54 months (range 3-149, median 3.3) after valvoplasty. These patients did not have a significant decrease in gradient after intervention. Their gradient subsequently decreased during follow-up and then became static before increasing years after intervention. In contrast, the gradient of patients not requiring further intervention continually reduced over time. Demographics did not differ between these groups.<bold>Conclusion: </bold>We could not identify predisposing factors for long-term success of pulmonary valvoplasty in Noonan's patients, but the trajectory of gradients differs significantly between patients needing re-intervention from those who remain free from re-intervention.
- Subjects
PULMONARY valve stenosis in children; NOONAN syndrome; PERCUTANEOUS balloon valvuloplasty; HEART disease diagnosis; JUVENILE diseases; THERAPEUTICS; CARDIAC catheterization; CATHETERIZATION; DOPPLER echocardiography; LONGITUDINAL method; PULMONARY stenosis; REOPERATION; SURGICAL complications; TIME; DISEASE incidence; RETROSPECTIVE studies; DISEASE complications; DIAGNOSIS
- Publication
Cardiology in the Young, 2018, Vol 28, Issue 5, p647
- ISSN
1047-9511
- Publication type
journal article
- DOI
10.1017/S1047951117002827