We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Depression in Childhood and Adolescence.
- Authors
Maughan, Barbara; Collishaw, Stephan; Stringaris, Argyris
- Abstract
Objective: To review recent evidence on child and adolescent depression. Method: Narrative review. Results: Rates of unipolar depression are low before puberty, but rise from the early teens, especially among girls. Concurrent comorbidity with both disruptive and emotional disorders is common, especially among younger children; across age, youth depression may be preceded by both anxiety and disruptive behaviour disorders, and increase risk for alcohol problems. Adolescent depression is associated with a range of adverse later outcomes including suicidality, problems in social functioning and poor physical and mental health. Across development, a family history of depression and exposure to stressful life events are the most robust risk factors for depression. Familial transmission involves both psychosocial and heritable processes; genetic and environmental influences also combine to influence risk. Neurocognitive and neuroendocrine pathways have been established, but contributors to the adolescent rise in risk, and the female preponderance later in development, remain to be clarified. Depressed youth benefit from psychological therapy or antidepressant medication or their combination; however, treatment effects are moderate. Conclusions: Despite considerable progress in understanding developmental trajectories to depression, more needs to be done to identify disease mechanisms that may serve as intervention targets early in the life course.
- Subjects
ETIOLOGY of diseases; EPIDEMIOLOGY; DEPRESSION in children; DEPRESSION in adolescence; ANTIDEPRESSANTS; MENTAL health; CHILD psychology; ADOLESCENCE; BEHAVIOR disorders in children
- Publication
Journal of the Canadian Academy of Child & Adolescent Psychiatry, 2013, Vol 22, Issue 1, p35
- ISSN
1719-8429
- Publication type
Article