The article presents the result of observations on the predatory behavior of the endemic Honduran Palm-Viper, Botrhiechis marchi sensu lato, in the cloud forest at Parque Nacional Cusuco in Honduras in 2013. The natural diet of the viper includes the Mexican deer mouse Peromyscus mexicanus, the tree-frog Plectrohyla dasypus, and the Mexican mouse opossum Marmosa mexicana. The geographic distribution of the genus Bothriechis is discussed.