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- Title
Detection by Three Cellular Immunological Techniques of the Antigenic Determinants of the Ly-Li System, Expressed on Human B Lymphocytes.
- Authors
Sasportes, M.; Mawas, C.; Crosier, P.; Charmot, D.; Legrand, I.; Dausset, J.
- Abstract
A clear correlation was observed between the presence of an Ia-like antigenic B-cell system Ly-Li. detected serologically, and three cellular immunological techniques: [1] mixed lymphocyte reaction (MLR) inhibition by an anti-Li antiserum; [2] level of restimulation of anti-Ly-Li in-vitro-primed lymphocytes; and [3] detection of HLA-D alleles by homozygous typing cells. These results suggested that the allelic products detected serologically may be identical to those detected by the first two techniques, namely MLR inhibition and in-vitro-primed lymphocyte typing, and, possibly, HLA-D typing using homozygous typing cells, although the correlation was repeatedly found to be less clear for the last technique.
- Subjects
LEUCOCYTES; ANTIGENS; IMMUNOGLOBULINS; SEROLOGY; LYMPHOCYTES; IMMUNOLOGY
- Publication
Scandinavian Journal of Immunology, 1977, Vol 6, Issue 5, p507
- ISSN
0300-9475
- Publication type
Article
- DOI
10.1111/j.1365-3083.1977.tb02112.x