We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Evaluation of the autonomic heart rate modulation of patients with chronic renal disease in hemodyalysis: preliminare study.
- Authors
Garbeto Rodrigues, Natália; de Albuquerque, José Augusto Félix; Medeiros Guio, Bruno; Silva Reis, Michel
- Abstract
Chronic kidney disease (CKD) is defined as damage to kidney function. Patients have high prevalence of death by cardiovascular events before the final stages of the disease, with higher mortality in dialytic stage, in which autonomic imbalance is evidenced. This study seeks to evaluate sympathovagal modulation of patients with CKD undergoing hemodialysis treatment. We evaluated 23 subjects, divided into: CDK-group with CKD-stage 5D in regular hemodialysis treatment; and Control-group with healthy individuals. Heart rate variability (HRV) was collected by a heart rate monitor and analyzed by linear time domain and frequency domain indices. CDK-group had 14 patients, mean age of 48±16; and Control-group had 9 healthy patients, mean age of 64±5. In the time domain, CDK-group showed significantly higher heart rate values compared with Control-group (83.49±13.09 bpm vs. 67.88±9.43 bpm). However, the mean indices of the R-R intervals (735.82±121.54 ms vs. 898.94±123.58 ms), RMSSD (11.75±11.86 ms vs. 20.03±6.80 ms), and SDNN (17.06±9.81 ms vs. 28.42±7.62 ms) from CDK-group showed significantly lower values compared with Control-group. In frequency domain results, CDK-group showed significantly lower values compared with Control-group in LFab (129.7±184.3 ms vs. 262.31±168.15 ms) and HFab (82.70±227.66 ms vs. 180.77±119.85 ms). Patients with CKD on hemodialysis had reduced parasympathetic modulation compared with healthy subjects, suggesting impairment of the sympathovagal balance and, consequently, cardiac autonomic dysfunction.
- Subjects
BRAZIL; CARDIOVASCULAR disease prevention; CHRONIC kidney failure; AUTONOMIC nervous system; CROSS-sectional method; MANN Whitney U Test; T-test (Statistics); HEART beat; DESCRIPTIVE statistics; HEMODIALYSIS; DATA analysis software
- Publication
Fisioterapia e Pesquisa, 2021, Vol 28, Issue 2, p151
- ISSN
1809-2950
- Publication type
Article
- DOI
10.1590/1809-2950/20001828022021