Back to matchesWe found a matchYour institution may have access to this item. Find your institution then sign in to continue.TitleSynthetic approaches to site selective deuterium incorporation in a novel CRTh2 receptor antagonist clinical candidate.AuthorsSandham, David A.; Page, Christopher J.AbstractSelection of acidic or basic reaction conditions, combined with appropriate temperatures, allowed for site selective direct incorporation of deuterium at multiple positions in the 7-azaindole-3-acetic acid CRTh2 receptor antagonist clinical candidate NVP-QAV680. Copyright © 2014 John Wiley & Sons, Ltd.SubjectsDEUTERATION; CHEMICAL reactions; CHEMICAL synthesis; TEMPERATURE; ACETIC acid; AZAINDOLESPublicationJournal of Labelled Compounds & Radiopharmaceuticals, 2014, Vol 57, Issue 3, p175ISSN0362-4803Publication typeOtherDOI10.1002/jlcr.3174