We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The Effect of Overhydration on Mortality and Technique Failure Among Peritoneal Dialysis Patients: A Systematic Review and Meta-Analysis.
- Authors
Shu, Ying; Liu, Jing; Zeng, Xiaoxi; Hong, Hyokyoung G.; Li, Yi; Zhong, Hui; Ma, Liang; Fu, Ping
- Abstract
Background: Overhydration is common among peritoneal dialysis (PD) patients and can affect PD-related outcomes. This paper aims to systematically investigate whether bioimpedance-assessed overhydration is a predictor for mortality and technique failure in PD patients. Methods: We conducted a systematic review and meta-analysis of cohort studies on overhydration and prognosis in PD patients, strictly complying with the Preferred Reporting Items for Systematical Reviews and Meta-analyses. Results: Eight articles met the selection criteria and 5 studies were included in the meta-analysis. Meta-analyses-revealed overhydration, defined as a high ratio of extracellular water/total body water (ECW/TBW), was significantly associated with higher risk for all-cause mortality and technique failure. Other higher dichotomized overhydration indicators and continuous hydration variables all indicated overhydration as a significant risk factor for all-cause mortality. Conclusion: Overhydration, defined by a higher ratio of ECW/TBW, might be an independent predictor for all-cause mortality and technique failure among PD patients. However, more studies are needed to confirm this conclusion. Video Journal Club 'Cappuccino with Claudio Ronco' at https://www.karger.com/Journal/ArticleNews/223997?sponsor=52
- Subjects
PERITONEAL dialysis; KIDNEY diseases; HEMODIALYSIS; WATER intoxication; ACUTE kidney failure
- Publication
Blood Purification, 2018, Vol 46, Issue 4, p350
- ISSN
0253-5068
- Publication type
Article
- DOI
10.1159/000492148