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- Title
Trajectories of the Psychological Status of Mothers of Infants With Nonsyndromic Orofacial Clefts: A Prospective Cohort Study From the Japan Environment and Children's Study.
- Authors
Sato, Yukihiro; Yoshioka, Eiji; Saijo, Yasuaki; Miyamoto, Toshinobu; Sengoku, Kazuo; Azuma, Hiroshi; Tanahashi, Yusuke; Ito, Yoshiya; Kobayashi, Sumitaka; Minatoya, Machiko; Bamai, Yu Ait; Yamazaki, Keiko; Ito, Sachiko; Miyashita, Chihiro; Araki, Atsuko; Kishi, Reiko
- Abstract
Objective: This study examined psychological status trajectories of mothers of infants with nonsyndromic orofacial clefts in Japan. Design: Prospective cohort study. Setting: Data from the Japan Environment and Children's Study. Participants: Infants with a nonsyndromic cleft (N = 148) including cleft lip and palate (CLP; n = 72), cleft lip (CL; n = 46), and cleft palate (CP; n = 30). The control group included unaffected infants (N = 84 454). Main Outcome Measures: At 15 weeks and 27 weeks of pregnancy and 12 months after birth, the Kessler Psychological Distress Scale (clinical cutoff ≥5) was used. At 1 month and 6 months after birth, the Edinburgh Postnatal Depression Scale (clinical cutoff ≥9) was used. Results: Prenatal diagnosis rates were unavailable. Mothers of infants with CLP had higher psychological distress than controls at 27 weeks of pregnancy (prevalence ratio [PR] = 1.36, 95% CI: 1.06-1.74) and postnatal depression at 1 month after birth (PR = 2.21, 95% CI: 1.53-3.19). Mothers of infants with CP showed heightened psychological distress at 27 weeks of pregnancy (PR = 1.62, 95% CI: 1.21-2.17) and postnatal depression 6 months after birth (PR = 1.86, 95% CI: 1.01-3.43). There was no significant association between CL and maternal psychological status. At 12 months after birth, no differences in distress were found between mothers of infants with a cleft and controls. Conclusions: Mothers of infants with orofacial clefts may need psychosocial support, particularly during pregnancy and the first year after birth.
- Subjects
JAPAN; CONFIDENCE intervals; FACIAL dyskinesias; LONGITUDINAL method; MOTHERS; PSYCHOLOGY of mothers; MOUTH abnormalities; NEUROMUSCULAR diseases; DESCRIPTIVE statistics
- Publication
Cleft Palate Craniofacial Journal, 2021, Vol 58, Issue 3, p369
- ISSN
1055-6656
- Publication type
Article
- DOI
10.1177/1055665620951399