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- Title
The challenges of differential diagnosis between pseudomyxoma peritonei and primary ovarian neoplasia. Case presentation and literature review.
- Authors
Vasilescu, Sorin; Meca, Daniela; Ţurcanu, Natalia; Munteanu, Octavian; Pariza, George; George, Simion; Pătraşcu, Oana; Cîrstoiu, Monica
- Abstract
Pseudomyxoma peritonei originates from primary mucinous neoplasms of the appendix or from different sites, especially the ovary. The specialized literature emphasizes the possibility of the existence of synchronous primary mucinous tumors of the ovary and appendix involved in the disease's onset. If untreated, the prognosis of the patients diagnosed with pseudomyxoma peritonei is fatal, due to the compression and blockage of the digestive tract. Ascites associates a poor prognosis through the characteristic pharmacoresistance, tumor cells in this context presenting genomic changes of acquired resistance across the whole genome. We report the case of a 61-year-old woman with massive ascites and pleurisy and atypical laboratory and intraoperative aspect, respectively peritoneal carcinomatosis, with infracentimetric disseminations on the epiploon, mesentery and parietal peritoneum. Also, a tumoral pelvic block which included the uterus, the ovaries, the sigmoid colon and ileal loops was detected. The extraabdominal spread of pseudomyxoma peritonei syndrome has a rare occurrence, with only few reports in literature. The differential diagnosis of primary tumor should be well established, because the misdiagnosis of a metastatic mucinous ovarian tumor as a primary neoplasia may adversely affect the surgical management, the complementary treatment and the prognosis.
- Subjects
MUCINOUS adenocarcinoma; OVARY abnormalities; CANCER prognosis; CANCER diagnosis; CANCER treatment
- Publication
Obstetrică şi Ginecologie, 2020, Vol 68, Issue 4, p204
- ISSN
1220-5532
- Publication type
Article
- DOI
10.26416/obsgin.68.4.2020.4034