We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
The First Decade with the Swedish Prescribed Drug Register - A Systematic Review of the Output in the Scientific Literature.
- Authors
Wallerstedt, Susanna M.; Wettermark, Björn; Hoffmann, Mikael
- Abstract
The aim of this study was to quantify and characterize the scientific output from the Swedish Prescribed Drug Register (SPDR) the first decade after its establishment. A systematic literature search was performed in Medline, EMBASE and PubMed (2005-2014). Additional publications were identified by personal knowledge, reference lists, contact with active authors and a citation search in Web of Sciences. Publications using SPDR data were included in the analysis and characterized regarding study type, presence of patient-level record linkage, target population and topic. A total of 719 publications were identified in the literature search and an additional 148 by other strategies. Three hundred and thirty-eight studies fulfilled the inclusion criteria. The majority were analytic (n = 166; 49.1%) or descriptive (n = 100; 29.5%). The remaining studies focused on validation (n = 20; 5.9%), health economics (n = 16; 4.7%) or miscellaneous (n = 36; 10.7%). The analytic studies investigating effects of drug exposure focused mainly on safety (n = 46) and/or effectiveness (n = 24). The first publications appeared in 2007 (n = 6), and in 2014, 90 articles using SPDR were published. Over the years, linkage with other registers using the personal identity number increased (0-88.9% of the publications). The population was often selected by age (49.7%), condition (45.0%) and/or drug (22.8%) and concerned predominantly psychiatric (29.0%) and cardiovascular (20.4%) diseases. In conclusion, this study illustrates that the establishment of a nationwide individual-based register on dispensed prescription drugs facilitates an encouraging development of pharmacoepidemiological research, both regarding the number of publications and the scientific level of the analyses.
- Subjects
MEDICAL economics; LINKAGE (Genetics); CARDIOVASCULAR diseases; DRUGS; PHARMACOEPIDEMIOLOGY
- Publication
Basic & Clinical Pharmacology & Toxicology, 2016, Vol 119, Issue 5, p464
- ISSN
1742-7835
- Publication type
Article
- DOI
10.1111/bcpt.12613