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- Title
The Evaluation of Serum Vitamin D Levels in Pediatric Patients With Vesicoureteral Reflux.
- Authors
Dabiri, Mona; Fatahibayat, Gholamali; Yousefichaijan, Parsa
- Abstract
Background and Aim:: Vesicoureteral Reflux (VUR) refers to the pathological return of urine from the bladder to the ureter and then to the kidney in some patients. Vitamin D deficiency is associated with some renal diseases. This study examines the relationship between vitamin D deficiency and urinary reflux. Methods: In this cross-sectional study, 200 children referred to Amir Kabir Hospital in Arak, Iran, were divided into 2 groups of patients with VUR (n=100) and another group of pediatric participants considered healthy and had no findings of VUR (n=100). Confirmation of diagnosis was performed via voiding cystourethrogram. Serum vitamin D levels were evaluated by the Enzyme-Linked Immunosorbent Assay (ELISA) method in all participants. Results: The results showed that the rate of vitamin D deficiency was 38% and 42% in the case and control groups, respectively. Therefore, no significant correlation was observed between the two study groups in terms of vitamin D deficiency. This finding was regardless of VUR complications affecting vitamin D metabolism. Conclusion: We assume that VUR is a complicated condition with several complications, and the relationship of each complication with vitamin D deficiency has been determined to some extent in previous studies; however, this condition cannot be considered an independent factor leading to vitamin D deficiency.
- Subjects
ARAK (Iran); VESICO-ureteral reflux; CHILD patients; VITAMIN D deficiency; VITAMIN D; VITAMIN D metabolism; ENZYME-linked immunosorbent assay
- Publication
Journal of Pediatric Nephrology, 2022, Vol 10, Issue 2, p91
- ISSN
2345-3176
- Publication type
Article
- DOI
10.22037/jpn.v10i2.38193