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- Title
Identification of Metabolism-Associated Biomarkers for Early and Precise Diagnosis of Oral Squamous Cell Carcinoma.
- Authors
Wang, Yuhan; Zhang, Xiaoxin; Wang, Shuai; Li, Zihui; Hu, Xinyang; Yang, Xihu; Song, Yuxian; Jing, Yue; Hu, Qingang; Ni, Yanhong
- Abstract
The 5-year survival rate for oral squamous cell carcinoma (OSCC), one of the most common head and neck cancers, has not improved in the last 20 years. Poor prognosis of OSCC is the result of failure in early and precise diagnosis. Metabolic reprogramming, including the alteration of the uptake and utilisation of glucose, amino acids and lipids, is an important feature of OSCC and can be used to identify its biomarkers for early and precise diagnosis. In this review, we summarise how recent findings of rewired metabolic networks in OSCC have facilitated early and precise diagnosis of OSCC.
- Subjects
SQUAMOUS cell carcinoma; EARLY diagnosis; HEAD &; neck cancer; BIOMARKERS
- Publication
Biomolecules (2218-273X), 2022, Vol 12, Issue 3, p400
- ISSN
2218-273X
- Publication type
Article
- DOI
10.3390/biom12030400