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- Title
Immediate administration of intravesical mitomycin C after tumour resection for superficial bladder cancer.
- Authors
Mostafid, A. Hugh; Rajkumar, Raj G. N.; Stewart, Alistair B.; Singh, Raj
- Abstract
OBJECTIVE To assess the feasibility and safety of administering intravesical mitomycin C in theatre immediately after transurethral resection of bladder tumour (TURBT). PATIENTS AND METHODS A protocol was developed to allow the safe administration of mitomycin C in theatre immediately after TURBT. Over a 32-month period all patients not excluded by the protocol were given mitomycin C in theatre after TURBT, and any adverse events reported. RESULTS In all, 177 instillations were carried out; there were two minor patient-related complications, and no staff-related adverse events. CONCLUSION The immediate administration of mitomycin C in theatre after TURBT is feasible and safe for patients and staff. It provides the earliest and surest prophylaxis against tumour cell re-implantation at TURBT.
- Subjects
MITOMYCIN C; FEASIBILITY studies; CANCER cells; BLADDER; DRUG therapy; META-analysis
- Publication
BJU International, 2006, Vol 97, Issue 3, p509
- ISSN
1464-4096
- Publication type
Article
- DOI
10.1111/j.1464-410X.2006.05965.x