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- Title
JC polyomavirus mutants escape antibody-mediated neutralization.
- Authors
Ray, Upasana; Cinque, Paola; Gerevini, Simonetta; Longo, Valeria; Lazzarin, Adriano; Schippling, Sven; Martin, Roland; Buck, Christopher B.; Pastrana, Diana V.
- Abstract
The article discusess the role of John Cunningham polyomavirus in developing progressive multifocal leukoencephalopathy (PML). Topics discussed include vaccination of JC polyomavirus for prevent the development of PML; immune response of the same; and use of enzyme-linked immunosorbent assay test for detecting serum antibodies in viral protein 1 associated with the same.
- Subjects
JOHN Cunningham virus; PROGRESSIVE multifocal leukoencephalopathy; VIRAL vaccines; IMMUNE response; ENZYME-linked immunosorbent assay; PREVENTION
- Publication
Science Translational Medicine, 2015, Vol 7, Issue 306, p1
- ISSN
1946-6234
- Publication type
Article
- DOI
10.1126/scitranslmed.aab1720