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- Title
Anti-staphylococcal effect of red roselle (Hibiscus sabdariffa L.) calyx decoction as an Indonesian folk medicine beverage.
- Authors
Fitri Kusuma, Sri Agung; Zuhrotun, Ade; Hendriani, Rini; Indrayati, Ana; Radianawati, Anita; Rukayadi, Yaya
- Abstract
The study was purposed to investigate the antibacterial effect of red roselle (Hibiscus sabdariffa L.) calyx decoction on Staphylococcus sp. growth inhibition that could be useful to overcome staphylococcal infection. Materials and Methods: The calyxes of the roselle were extracted using the decoction method by boiling fresh red roselle calyxes until the temperature reached 90°C for 30 min. The antibacterial effect of the decoct was tested against Staphylococcus aureus ATCC 11784, Staphylococcus epidermidis ATCC 13228, Staphylococcus warneri ATCC 3340, and Staphylococcus xylosus ATCC 3342 using the agar diffusion method. The minimum inhibitory concentration value (MIC) was done using the agar macrodilution method. The antibacterial of the decoct then compared to tetracycline Hydrochloride (HCl). Results: The roselle decoct possessed the antibacterial activity with broad spectrum against all tests Staphylococcus in dilutions ranging from 0.41 to 0.81% w/v, except the MIC against S. aureus 11,748, reached the highest MIC value at 0.81–1.62% w/v. The anti-staphylococcal comparison values of roselle decoct against tetracycline HCl were S. aureus (1:5.67), S. epidermidis (1:1.10), S. warneri (1:1.24), and S. xylosus (1:5.04). Conclusion: This study indicated clear evidence supporting the red roselle calyx in the decoct preparation use in treating staphylococcal infection-related to bacteria.
- Subjects
ROSELLE; TRADITIONAL medicine; STAPHYLOCOCCAL diseases; STAPHYLOCOCCUS epidermidis; STAPHYLOCOCCUS aureus; STAPHYLOCOCCUS; MICROCOCCACEAE
- Publication
Drug Invention Today, 2020, Vol 13, Issue 5, p719
- ISSN
0975-7619
- Publication type
Article