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- Title
Overview of makers for apoptosis.
- Authors
Satwik, T. Akshay; Ramasubramanium, Abilasha; Sathiyawathie, R. Sarah
- Abstract
The various markers for the apoptosis pathway reviewed in this article are DNA fragmentation, caspase activation, bid cleavage, and cytochrome c release. Apoptosis is a pathway of programmed cell death that may occur in multicellular organisms. Biochemical events leads to characteristics cell changes and death. The apoptosis assays, based on methodology, are of six groups cytomorphological alterations, DNA fragmentation, detection of caspases, cleaved substrate, regulators and inhibitors, membrane alterations, detection of apoptosis in whole mounts, mitochondrial assays.
- Subjects
APOPTOSIS; CYTOCHROME c; CELL death
- Publication
Drug Invention Today, 2019, Vol 12, Issue 3, p854
- ISSN
0975-7619
- Publication type
Article