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- Title
A review of perioperative corticosteroid use in oral and maxillofacial surgery.
- Authors
Sri, S. Bavana; Sathiyawathie, R. Sarah; Gurunathan, Deepa
- Abstract
Aim: Oral and maxillofacial surgeons are often recommended to use corticosteroids during and after third molar extraction and other dentoalveolar surgical procedures to reduce postsurgical edema, but recommendations are rarely accompanied by the guidance regarding the type of steroid, dosage, or duration of administration. Materials and Methods: A systematic search of the literature was made. The primary predictor variable was CS administration, and the outcome variables were edema, pain, and infection. A meta-analysis was performed. The risk of other side effects was evaluated through a simple review. Results: Recent data suggest that perioperative corticosteroid regimens should be administered in higher doses and for longer durations than recommended in the past and should be started before surgery for optimum benefit. Conclusions: Based on literature review, interim recommendations for the use of corticosteroids are proposed, including dosages and regimens that appear rational for oral, intramuscular, or intravenous corticosteroid administration before and after extractions and other dentoalveolar surgery. These largely empiric recommendations might require adjustment when evidence-based data become available in future studies. There is a great need for well-designed clinical research to further evaluate protocols for corticosteroid use.
- Subjects
MAXILLOFACIAL surgery; ORAL surgery; DRUG side effects; OPERATIVE surgery; SURGICAL enucleation
- Publication
Drug Invention Today, 2019, Vol 12, Issue 3, p611
- ISSN
0975-7619
- Publication type
Article