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- Title
Summary of Proceedings and Expert Consensus Statements From the International Summit "Lipids in Parenteral Nutrition".
- Authors
Martindale, Robert G.; Berlana, David; Boullata, Joseph I.; Cai, Wei; Calder, Philip C.; Deshpande, Girish H.; Evans, David; Garcia‐de‐Lorenzo, Abelardo; Goulet, Olivier J.; Li, Ang; Mayer, Konstantin; Mundi, Manpreet S.; Muscaritoli, Maurizio; Pradelli, Lorenzo; Rosenthal, Martin; Seo, Jeong‐Meen; Waitzberg, Dan L.; Klek, Stanislaw; Garcia-de-Lorenzo, Abelardo; Seo, Jeong-Meen
- Abstract
<bold>Background: </bold>The 2018 Lipids in Parenteral Nutrition summit involved a panel of experts in clinical nutrition, lipid metabolism, and pharmacology, to assess the current state of knowledge and develop expert consensus statements regarding the use of intravenous lipid emulsions in various patient populations and clinical settings. The main purpose of the consensus statements is to assist healthcare professionals by providing practical guidance on common clinical questions related to the provision of lipid emulsions as part of parenteral nutrition (PN).<bold>Methods: </bold>The summit was designed to allow interactive discussion and consensus development. The resulting consensus statements represent the collective opinion of the members of the expert panel, which was informed and supported by scientific evidence and clinical experience.<bold>Results: </bold>The current article summarizes the key discussion topics from the summit and provides a set of consensus statements designed to complement existing evidence-based guidelines. Lipid emulsions are a major component of PN, serving as a condensed source of energy and essential fatty acids. In addition, lipids modulate a variety of biologic functions, including inflammatory and immune responses, coagulation, and cell signaling. A growing body of evidence suggests that lipid emulsions containing ω-3 fatty acids from fish oil confer important clinical benefits via suppression of inflammatory mediators and activation of pathways involved in the resolution of inflammation.<bold>Conclusions: </bold>This article provides a set of expert consensus statements to complement formal PN guideline recommendations.
- Subjects
PARENTERAL feeding; INTRAVENOUS fat emulsions; ESSENTIAL fatty acids; LIPIDS; LIPID metabolism; SOY oil; RESEARCH funding; FISH oils
- Publication
JPEN Journal of Parenteral & Enteral Nutrition, 2020, Vol 44, pS7
- ISSN
0148-6071
- Publication type
journal article
- DOI
10.1002/jpen.1746