We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
A Phase 2 Trial Exploring the Effects of High-Dose (10,000 lU/Day) Vitamin D<sub>3</sub> in Breast Cancer Patients With Bone Metastases.
- Authors
Amir, Eitan; Simmons, Christine E.; Freedman, Orit C.; Dranitsaris, George; Cole, David E. C.; Vieth, Reinhold; Ooi, Wei S.; Clemons, Mark
- Abstract
The article presents a study which evaluates the effect of a 10,000-IU oral dose of vitamin D3 in patients with bone metastases from breast cancer. It says that 40 patients with bone metastases treated with bisphosphonates receive 10,000 IU of vitamin D3 and 1000 mg of calcium supplementation for four months. Result shows that despite significant increase in serum calcium and decrease in serum parathyroid hormone, there are no significant changes in bone resorption markers.
- Subjects
CHOLECALCIFEROL; BONE metastasis; BREAST cancer patients; PARATHYROID hormone; BONE resorption; DIPHOSPHONATES; BONE physiology; THERAPEUTICS
- Publication
Cancer (0008543X), 2010, Vol 116, Issue 2, p284
- ISSN
0008-543X
- Publication type
Article
- DOI
10.1002/cncr.24749