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- Title
CLINICAL PROFILE, POTENTIAL THERAPIES AND PSYCHOLOGICAL IMPACT OF VITILIGO IN CHILDREN AND ADOLESCENTS.
- Authors
Maqsood, Noshaba; Bashir, Mahpara; Sherazi, Bushra Ali
- Abstract
Background: Vitiligo is a persistent acquired depigmentary disease of the skin which is provoked by melanocyte demoliation and has a multifactorial pathogenesis with autoimmunity playing a major role in the onset of disease. Objective: To determine the clinical patterns, treatment options and stressful life events triggered by vitiligo in children and adolescents in order to outline the main attributes of this disease in Lahore. Methods: A retrospective evaluation of 50 medical records of patients with vitiligo was done at the Services Hospital Lahore and Sir Ganga Ram Hospital Lahore during August 2016 to September 2016 by random sampling technique. Results: The mean age of emergence of vitiligo in children and adolescents was 7 years and in patients with a first-degree family history of vitiligo, the disease arose more frequently. Vitiligo was commonly syndicated with other autoimmune diseases. The most extensively used first line treatment for vitiligo was topical corticosteroids and topical calcineurin inhibitors. Light therapieswere used primarily in conjunction with topical corticosteroids, vitamin D analogues, azathioprine and others. The most of combination therapies have both revealed increased repigmentation and have been demonstrated to be the most effective. Conclusion: The most important finding of this study is that localized vitiligo was the most prevailing type of vitiligo in our study sample. It was concluded that treatment of vitiligo is dependent on subtype and age and proper knowledge and psychological assistance of the victim and his/her parents is of extreme significance.
- Subjects
MELANOCYTES; VITILIGO; ADRENOCORTICAL hormones; AZATHIOPRINE; JUVENILE diseases; PSYCHOLOGY; THERAPEUTICS
- Publication
Medical Channel, 2017, Vol 23, Issue 1, p78
- ISSN
1681-5491
- Publication type
Article