The article focuses on the diagnosis and management of immunoglobulin light-chain (AL) amyloidosis. It says that diagnosis of AL amyloidosis should be considered in patients who presents with symptoms including gastronintestinal (GI) bleeding or mucosa, skin thickening, and calcific lymphadenopathy. It mentions that autologous stem-cell transplantation (HDM/SCT) ands high-dose melphalan give significant benefits to amyloidosis patients.