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- Title
Papillomavirus-like Particles in Equine Medicine.
- Authors
Hainisch, Edmund K.; Jindra, Christoph; Kirnbauer, Reinhard; Brandt, Sabine
- Abstract
Papillomaviruses (PVs) are a family of small DNA tumor viruses that can induce benign lesions or cancer in vertebrates. The observation that animal PV capsid-proteins spontaneously self-assemble to empty, highly immunogenic virus-like particles (VLPs) has led to the establishment of vaccines that efficiently protect humans from specific PV infections and associated diseases. We provide an overview of PV-induced tumors in horses and other equids, discuss possible routes of PV transmission in equid species, and present recent developments aiming at introducing the PV VLP-based vaccine technology into equine medicine.
- Subjects
ONCOGENIC DNA viruses; PAPILLOMAVIRUSES; VIRUS-like particles; DISEASE complications; EQUIDAE
- Publication
Viruses (1999-4915), 2023, Vol 15, Issue 2, p345
- ISSN
1999-4915
- Publication type
Article
- DOI
10.3390/v15020345