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- Title
Occurrence of antinuclear antibodies in an unselected pregnancy population.
- Authors
Kiuttu, Jorma; Hartikainen-Sorri, Anna-Liisa; Mäkitalo, Reino; Kiuttu, J; Hartikainen-Sorri, A L; Mäkitalo, R
- Abstract
The occurrence of antinuclear antibodies (ANA) in an unselected population of pregnant women was studied by an indirect immunofluorescence method. Six women out of 116 were ANA-positive (5.2%), 2 of them having a moderately high titre (1:160 and 1:320) and 1 complement-fixing ANA. The antigenic specificity of ANA was anti-single-stranded DNA in 2 cases and RNAase-sensitive anti-extractable nuclear antigen in 1 case. Two of the ANA-positive women had pre-eclampsia laevis and 1 had a premature delivery. None of the infants of the ANA-positive women had symptoms of connective tissue disease. The occurrence of ANA among pregnant women was not significantly higher than among 70 non-pregnant female control subjects (7.1%).
- Subjects
FINLAND; AUTOANTIBODY analysis; IMMUNOGLOBULIN analysis; AUTOANTIBODIES; COMPARATIVE studies; COMPLEMENT fixation; DNA; FLUORESCENT antibody technique; HEMAGGLUTINATION tests; IMMUNOGLOBULINS; PREMATURE labor; RESEARCH methodology; MEDICAL cooperation; PREECLAMPSIA; RESEARCH; EVALUATION research; PARITY (Obstetrics)
- Publication
Gynecologic & Obstetric Investigation, 1992, Vol 33, Issue 1, p21
- ISSN
0378-7346
- Publication type
journal article
- DOI
10.1159/000294841