We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Relationship between Baseline Serum Potassium and 1-Year Readmission in Pediatric Patients with Heart Failure: A Retrospective Cohort Study.
- Authors
Han, Yong; Huang, Yuqin; Su, Danyan; Liu, Dongli; Chen, Cheng; Pang, Yusheng
- Abstract
Pediatric heart failure (HF) is associated with high readmission rates, but the optimal serum potassium range for this population remains unclear. In this single-center retrospective cohort study, 180 pediatric patients hospitalized for HF between January 2016 and January 2022 were stratified into low-potassium (<3.7 mmol/L), middle-potassium (3.7–4.7 mmol/L), and high-potassium (≥4.7 mmol/L) groups based on the distribution of potassium levels in the study population. The primary outcome was readmission for HF within 1 year of discharge. Cox regression and restricted cubic spline models were used to assess the association between potassium levels and 1-year HF readmission rates. Notably, 38.9% of patients underwent 1 or more 1-year readmissions for HF within 1 year. The high-potassium group had a significantly higher readmission frequency than the middle-potassium group. In multivariate Cox regression models, potassium levels of ≥4.7 mmol/L were independently associated with increased 1-year readmission risk. A J-shaped relationship was observed between baseline potassium levels and 1-year readmission risk, with the lowest risk at 4.1 mmol/L. In pediatric patients with HF, a serum potassium level ≥ 4.7 mmol/L was independently associated with increased 1-year readmission risk. Maintaining potassium levels within a narrow range may improve outcomes in this population.
- Subjects
RISK assessment; RECEIVER operating characteristic curves; POTASSIUM; PATIENT readmissions; HYPERKALEMIA; KRUSKAL-Wallis Test; HEART failure; RETROSPECTIVE studies; DESCRIPTIVE statistics; CHI-squared test; LONGITUDINAL method; KAPLAN-Meier estimator; LOG-rank test; MEDICAL records; ACQUISITION of data; ONE-way analysis of variance; CONFIDENCE intervals; DATA analysis software; TIME; REGRESSION analysis; PROPORTIONAL hazards models; DISEASE complications; CHILDREN
- Publication
Children, 2024, Vol 11, Issue 6, p725
- ISSN
2227-9067
- Publication type
Article
- DOI
10.3390/children11060725