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- Title
Review of HIV Self Testing Technologies and Promising Approaches for the Next Generation.
- Authors
Bacon, Amanda; Wang, Weijing; Lee, Hankeun; Umrao, Saurabh; Sinawang, Prima Dewi; Akin, Demir; Khemtonglang, Kodchakorn; Tan, Anqi; Hirshfield, Sabina; Demirci, Utkan; Wang, Xing; Cunningham, Brian T.
- Abstract
The ability to self-test for HIV is vital to preventing transmission, particularly when used in concert with HIV biomedical prevention modalities, such as pre-exposure prophylaxis (PrEP). In this paper, we review recent developments in HIV self-testing and self-sampling methods, and the potential future impact of novel materials and methods that emerged through efforts to develop more effective point-of-care (POC) SARS-CoV-2 diagnostics. We address the gaps in existing HIV self-testing technologies, where improvements in test sensitivity, sample-to-answer time, simplicity, and cost are needed to enhance diagnostic accuracy and widespread accessibility. We discuss potential paths toward the next generation of HIV self-testing through sample collection materials, biosensing assay techniques, and miniaturized instrumentation. We discuss the implications for other applications, such as self-monitoring of HIV viral load and other infectious diseases.
- Subjects
DIAGNOSIS of HIV infections; PATIENT self-monitoring; HIV; HIV testing kits; VIRAL load; HIV prevention; PRE-exposure prophylaxis
- Publication
Biosensors (2079-6374), 2023, Vol 13, Issue 2, p298
- ISSN
2079-6374
- Publication type
Article
- DOI
10.3390/bios13020298