We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Possible Involvement of Hyperlipidemia in Increasing Risk of Colorectal Tumor Development in Human Familial Adenomatous Polyposis.
- Authors
Mutoh, Michihiro; Akasu, Takayuki; Takahashi, Mami; Niho, Naoko; Yoshida, Teruhiko; Sugimura, Takashi; Wakabayashi, Keiji
- Abstract
Background: Familial adenomatous polyposis (FAP) results from germline adenomatous polyposis coli (APC) gene mutations and many affected patients die from colorectal cancers which arise from colorectal polyps. We previously reported that two strains of Apc gene-deficient mice developing multiple intestinal polyps exhibit a hyperlipidemic state. The triglyceride (TG) levels were ∼10-fold higher than the levels observed in wild-type mice.
- Publication
Japanese Journal of Clinical Oncology, 2006, Vol 36, Issue 3, p166
- ISSN
0368-2811
- Publication type
Article
- DOI
10.1093/jjco/hyi233