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- Title
Estimates of Genomic Heritability and the Marker-Derived Gene for Re(Production) Traits in Xinggao Sheep.
- Authors
Liu, Zaixia; Fu, Shaoyin; He, Xiaolong; Liu, Xuewen; Shi, Caixia; Dai, Lingli; Wang, Biao; Chai, Yuan; Liu, Yongbin; Zhang, Wenguang
- Abstract
Xinggao sheep are a breed of Chinese domestic sheep that are adapted to the extremely cold climatic features of the Hinggan League in China. The economically vital reproductive trait of ewes (litter size, LS) and productive traits of lambs (birth weight, BWT; weaning weight, WWT; and average daily gain, ADG) are expressed in females and later in life after most of the selection decisions have been made. This study estimated the genetic parameters for four traits to explore the genetic mechanisms underlying the variation, and we performed genome-wide association study (GWAS) tests on a small sample size to identify novel marker trait associations (MTAs) associated with prolificacy and growth. We detected two suggestive significant single-nucleotide polymorphisms (SNPs) associated with LS and eight significant SNPs for BWT, WWT, and ADG. These candidate loci and genes also provide valuable information for further fine-mapping of QTLs and improvement of reproductive and productive traits in sheep.
- Subjects
CHINA; EWES; HERITABILITY; SHEEP; SHEEP breeds; GENOME-wide association studies; SINGLE nucleotide polymorphisms; SHEEP breeding
- Publication
Genes, 2023, Vol 14, Issue 3, p579
- ISSN
2073-4425
- Publication type
Article
- DOI
10.3390/genes14030579