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- Title
A comparative study of post-operative analgesic efficacy of dexmedetomidine 25 µg versus dexamethasone 2 mg used as an adjuvant with 20 ml 0.25% ropivacaine in bilateral superficial cervical plexus block for thyroidectomy under general anaesthesia -- a prospective randomized double blinded study.
- Authors
Pujari, Pranav; Saxena, Rahul
- Abstract
Introduction: The bilateral superficial cervical plexus block (BSCPB) is effective for postoperative analgesia following thyroid surgeries. We compared the efficacy of dexmedetomidine and dexamethasone used as an adjuvant with 0.25% ropivacaine in BSCPB for thyroidectomy under general anaesthesia with regards to the duration of analgesia, total amount of rescue analgesic requirement, changes in intra and post operative haemodynamic parameters, VAS scores and adverse events, if any. Methods: In this prospective double blinded study, 40 adults undergoing thyroidectomy were randomized into two equal groups and given BSCPB with 20 ml 0.25% ropivacaine with adjuvants as either dexmedetomidine 25 μg (Group A) or dexamethasone 2 mg (Group B), 10 ml on each side, after the induction of general anaesthesia. Visual analogue scale (VAS) was used for monitoring postoperative pain and the duration of analgesia. Postoperative haemodynamics parameters and any adverse events were recorded. Results: The mean duration of analgesia in group A was slightly prolonged but statistically non-significant as compared to group B (15.39 ± 1.61 vs. 13.15 ± 2.11 hours; p>0.05). The postoperative VAS scores and haemodynamics were comparable for both the groups (p>0.05). Group B reported significant decrease in the incidence of PONV (p<0.05). Conclusion: Although, dexamethasone offers a slight advantage of decreased incidence of PONV and cost effectiveness, BSCPB using ropivacaine with either dexmedetomidine or dexamethasone as an adjuvant imparted superior analgesia with stable haemodynamics and may be used as a pre-emptive analgesic technique in thyroid surgeries.
- Subjects
CERVICAL plexus; THYROIDECTOMY; ROPIVACAINE; DEXMEDETOMIDINE; DEXAMETHASONE; VISUAL analog scale
- Publication
Journal of Cardiovascular Disease Research (Journal of Cardiovascular Disease Research), 2024, Vol 15, Issue 6, p470
- ISSN
0975-3583
- Publication type
Article