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- Title
Hepatocyte Growth Factor And Periodontal Disease.
- Authors
Singh, Amrinder; Tuli, Avantika; Chaudhry, Kalpna; Sharma, Rohit
- Abstract
Hepatocyte growth factor (HGF) is one of the various chemical factors that facilitate periodontal destruction. HGF affects nervous system, immune system and reticuloendothelial system. It is a protein secreted by mesenchymal cells such as fibroblasts, and promotes motility and matrix invasion of epithelial cells. HGF - a pluripotential regenerative cytokine - is a key factor in the pathogenesis and progression of periodontal disease, mostly through its over-stimulation of gingival epithelial cell growth and impairment of the regeneration of collagenous structures.
- Subjects
PERIODONTAL disease; HEPATOCYTE growth factor; ORAL diseases; GROWTH factors; GROWTH
- Publication
Indian Journal of Dental Sciences, 2012, Vol 4, Issue 5, p90
- ISSN
0976-4003
- Publication type
Article