We found a match
Your institution may have access to this item. Find your institution then sign in to continue.
- Title
Factors Associated with Premature Hair Graying in a Young Indian Population.
- Authors
Chakrabarty, Swagata; Krishnappa, Prafulla G.; Gowda, Dinesh G.; Hiremath, Jyothi
- Abstract
Context: Although the primary cause of premature hair graying (PHG) is considered to be genetic, certain environmental factors also play a role. Trace element deficiencies such as Vitamin B12, Vitamin D3, and calcium may also be associated with PHG. However, India-specific data are relatively sparse. Aims: The present study aimed at identifying factors associated with PHG in Indian patients. Settings and Design: A case-control study was conducted at a trichology clinic in Bengaluru between October 2013 and April 2014 with a total of 37 cases of PHG and 37 age-and gender-matched controls. Materials and Methods: A total of 100 subjects were investigated for various parameters such as hemoglobin, serum ferritin, zinc, copper, calcium, Vitamin B12, and Vitamin D after obtaining informed consent. Statistical Analysis Used: Chi-square test was used to compare proportions between groups. Means were compared between groups using Student's t-test. Results: Serum ferritin levels were lower in patients with PHG as compared to the control group and the differences were statistically significant (P < 0.001). Furthermore, as compared to the controls, patients with PHG had lower serum Vitamin B12 levels (P < 0.001). Individuals with PHG had significantly lower levels of high-density lipoprotein cholesterol (HDL-C) as compared to the control group (P < 0.001). Significant proportions of patients with PHG had a sedentary lifestyle and admitted to having irregular eating habits. Conclusion: PHG is associated with low serum ferritin, Vitamin B12, and HDL-C levels in Indian patients aged <25 years. However, studies with large sample sizes may be required to conclusively define these putative associations.
- Subjects
GRAY hair; HAIR cell regeneration; TRACE elements; VITAMIN B12; CHOLECALCIFEROL; CHI-squared test; FERRITIN; HUMAN hair color
- Publication
International Journal of Trichology, 2016, Vol 8, Issue 1, p11
- ISSN
0974-7753
- Publication type
Article
- DOI
10.4103/0974-7753.179384