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- Title
A Case of α-Gal-Unrelated Red Meat-Induced Urticaria Treated by Omalizumab.
- Authors
Kondo, Makoto; Matsushima, Yoshiaki; Iida, Shohei; Umaoka, Ai; Nakanishi, Takehisa; Habe, Koji; Yamanaka, Keiichi
- Abstract
A 70-year-old healthy woman was referred to our hospital for chronic urticaria. She did not have a history of allergy, asthma, and rhinitis. She was initially diagnosed with α-gal-related urticaria based on an episode of delayed-type urticaria after eating red meat. The results of the intracutaneous allergen test for beef and pork were negative. Fluorenzyme immunoassays specific for IgE against α-gal, beef, and pork were also negative. She was diagnosed with an α-gal-unrelated red meat allergy following the reproduction of urticaria by a food challenge test. The patient was unresponsive to several drugs, including antihistamines or immunosuppressants. However, omalizumab administration suppressed her symptoms. Key Clinical Message: The diagnosis of red meat allergy may require a repeatability test by consuming red meat even though serum α-gal IgE antibody might be negative. The α-gal-unrelated red meat urticaria may be responsive to omalizumab.
- Subjects
URTICARIA; FOOD allergy; OMALIZUMAB; IMMUNOGLOBULIN E; IMMUNOASSAY; RHINITIS
- Publication
Case Reports in Dermatology, 2021, Vol 13, Issue 3, p437
- ISSN
1662-6567
- Publication type
Case Study
- DOI
10.1159/000518421