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Enhanced response rate to pegylated liposomal doxorubicin in high grade serous ovarian carcinomas harbouring BRCA1 and BRCA2 aberrations.
Published in:
2018
By:
- Hollis, Robert L.;
- Meynert, Alison M.;
- Churchman, Michael;
- Rye, Tzyvia;
- Mackean, Melanie;
- Nussey, Fiona;
- Arends, Mark J.;
- Sims, Andrew H.;
- Semple, Colin A.;
- Herrington, C. Simon;
- Gourley, Charlie
Publication type:
journal article
Distinct histopathological features are associated with molecular subtypes and outcome in low grade serous ovarian carcinoma.
Published in:
Scientific Reports, 2023, v. 13, n. 1, p. 1, doi. 10.1038/s41598-023-34627-5
By:
- Hollis, Robert L.;
- Thomson, John P.;
- van Baal, Juliette;
- Ilenkovan, Narthana;
- Churchman, Michael;
- van de Vijver, Koen;
- Dijk, Frederike;
- Meynert, Alison M.;
- Bartos, Clare;
- Rye, Tzyvia;
- Croy, Ian;
- Diana, Patricia;
- van Gent, Mignon;
- Creedon, Helen;
- Nirsimloo, Rachel;
- Lok, Christianne;
- Gourley, Charlie;
- Herrington, C. Simon
Publication type:
Article
In situ analysis of LKB1/STK11 mRNA expression in human normal tissues and tumours.
Published in:
Journal of Pathology, 2000, v. 192, n. 2, p. 203, doi. 10.1002/1096-9896(2000)9999:9999<::AID-PATH686>3.0.CO;2-J
By:
- Rowan, Andrew;
- Churchman, Michael;
- Jefferey, Rosemary;
- Hanby, Andrew;
- Poulsom, Richard;
- Tomlinson, Ian
Publication type:
Article
Meta-analysis of three genome-wide association studies identifies susceptibility loci for colorectal cancer at 1q41, 3q26.2, 12q13.13 and 20q13.33.
Published in:
Nature Genetics, 2010, v. 42, n. 11, p. 973, doi. 10.1038/ng.670
By:
- Houlston, Richard S.;
- Cheadle, Jeremy;
- Dobbins, Sara E.;
- Tenesa, Albert;
- Jones, Angela M.;
- Howarth, Kimberley;
- Spain, Sarah L.;
- Broderick, Peter;
- Domingo, Enric;
- Farrington, Susan;
- Prendergast, James G. D.;
- Pittman, Alan M.;
- Theodoratou, Evi;
- Smith, Christopher G.;
- Olver, Bianca;
- Walther, Axel;
- Barnetson, Rebecca A.;
- Churchman, Michael;
- Jaeger, Emma E. M.;
- Penegar, Steven
Publication type:
Article
Identifying and overcoming a mechanism of resistance to WEE1 kinase inhibitor AZD1775 in high grade serous ovarian cancer cells.
Published in:
European Journal of Gynaecological Oncology, 2022, v. 43, n. 2, p. 183, doi. 10.31083/j.ejgo4302024
By:
- Gomez, Miriam K.;
- Thomson, John P.;
- Grimes, Graeme R.;
- Wang, Anderson T.;
- Churchman, Michael;
- O'Connor, Mark J.;
- Gourley, Charlie;
- Melton, David W.
Publication type:
Article
The survival benefit associated with complete macroscopic resection in epithelial ovarian cancer is histotype specific.
Published in:
JNCI Cancer Spectrum, 2024, v. 8, n. 4, p. 1, doi. 10.1093/jncics/pkae049
By:
- Porter, Joanna M;
- McFarlane, Iona;
- Bartos, Clare;
- Churchman, Michael;
- May, James;
- Herrington, C Simon;
- Connolly, Kathryn C;
- Ryan, Neil A J;
- Hollis, Robert L
Publication type:
Article
The molecular origin and taxonomy of mucinous ovarian carcinoma.
Published in:
Nature Communications, 2019, v. 10, n. 1, p. N.PAG, doi. 10.1038/s41467-019-11862-x
By:
- Cheasley, Dane;
- Wakefield, Matthew J.;
- Ryland, Georgina L.;
- Allan, Prue E.;
- Alsop, Kathryn;
- Amarasinghe, Kaushalya C.;
- Ananda, Sumitra;
- Anglesio, Michael S.;
- Au-Yeung, George;
- Böhm, Maret;
- Bowtell, David D. L.;
- Brand, Alison;
- Chenevix-Trench, Georgia;
- Christie, Michael;
- Chiew, Yoke-Eng;
- Churchman, Michael;
- DeFazio, Anna;
- Demeo, Renee;
- Dudley, Rhiannon;
- Fairweather, Nicole
Publication type:
Article
Clinicopathological Determinants of Recurrence Risk and Survival in Mucinous Ovarian Carcinoma.
Published in:
Cancers, 2021, v. 13, n. 22, p. 5839, doi. 10.3390/cancers13225839
By:
- Hollis, Robert L.;
- Stillie, Lorna J.;
- Hopkins, Samantha;
- Bartos, Clare;
- Churchman, Michael;
- Rye, Tzyvia;
- Nussey, Fiona;
- Fegan, Scott;
- Nirsimloo, Rachel;
- Inman, Gareth J.;
- Herrington, C. Simon;
- Gourley, Charlie
Publication type:
Article
Identifying and Overcoming Mechanisms of PARP Inhibitor Resistance in Homologous Recombination Repair-Deficient and Repair-Proficient High Grade Serous Ovarian Cancer Cells.
Published in:
Cancers, 2020, v. 12, n. 6, p. 1503, doi. 10.3390/cancers12061503
By:
- Gomez, Miriam K.;
- Illuzzi, Giuditta;
- Colomer, Carlota;
- Churchman, Michael;
- Hollis, Robert L.;
- O'Connor, Mark J.;
- Gourley, Charlie;
- Leo, Elisabetta;
- Melton, David W.
Publication type:
Article
In vitro functional effects of XPC gene rare variants from bladder cancer patients.
Published in:
Carcinogenesis, 2011, v. 32, n. 4, p. 516, doi. 10.1093/carcin/bgr005
By:
- Qiao, Boling;
- Ansari, Abdul-Haq;
- Scott, Gina B.;
- Sak, Sei C.;
- Chambers, Philip A.;
- Elliott, Faye;
- Teo, Mark T.W.;
- Bentley, Johanne;
- Churchman, Michael;
- Hall, Janet;
- Taylor, Claire F.;
- Bishop, Timothy D.;
- Knowles, Margaret A.;
- Kiltie, Anne E.
Publication type:
Article
Before Chinese and Vietnamese in the Red River Plain: The Han-Tang Period.
Published in:
Chinese Southern Diaspora Studies, 2010, v. 4, p. 25
By:
- Churchman, Michael
Publication type:
Article
Compartment-specific multiomic profiling identifies SRC and GNAS as candidate drivers of epithelial-to-mesenchymal transition in ovarian carcinosarcoma.
Published in:
British Journal of Cancer, 2024, v. 130, n. 2, p. 327, doi. 10.1038/s41416-023-02508-3
By:
- Herrington, C. Simon;
- Oswald, Ailsa J.;
- Stillie, Lorna J.;
- Croy, Ian;
- Churchman, Michael;
- Hollis, Robert L.
Publication type:
Article
Ovarian carcinosarcoma is a distinct form of ovarian cancer with poorer survival compared to tubo-ovarian high-grade serous carcinoma.
Published in:
2022
By:
- Hollis, Robert L.;
- Croy, Ian;
- Churchman, Michael;
- Bartos, Clare;
- Rye, Tzyvia;
- Gourley, Charlie;
- Herrington, C. Simon
Publication type:
journal article
Intronic sequence variants of the CDKN2A gene in melanoma pedigrees.
Published in:
Genes, Chromosomes & Cancer, 2005, v. 43, n. 2, p. 128, doi. 10.1002/gcc.20177
By:
- Mark Harland;
- Claire F. Taylor;
- Sylvia Bass;
- Michael Churchman;
- Juliette A. Randerson-Moor;
- Elizabeth A. Holland;
- Graham J. Mann;
- D. Timothy Bishop;
- Julia A. Newton Bishop
Publication type:
Article
Integrated molecular characterisation of endometrioid ovarian carcinoma identifies opportunities for stratification.
Published in:
NPJ Precision Oncology, 2021, v. 5, n. 1, p. 1, doi. 10.1038/s41698-021-00187-y
By:
- Hollis, Robert L.;
- Stanley, Barbara;
- Thomson, John P.;
- Churchman, Michael;
- Croy, Ian;
- Rye, Tzyvia;
- Bartos, Clare;
- Nussey, Fiona;
- Mackean, Melanie;
- Meynert, Alison M.;
- Semple, Colin A.;
- Gourley, Charlie;
- Herrington, C. Simon
Publication type:
Article
High EMSY expression defines a BRCA-like subgroup of high-grade serous ovarian carcinoma with prolonged survival and hypersensitivity to platinum.
Published in:
2019
By:
- Hollis, Robert L.;
- Churchman, Michael;
- Michie, Caroline O.;
- Rye, Tzyvia;
- Knight, Laura;
- McCavigan, Andrena;
- Perren, Timothy;
- Williams, Alistair R. W.;
- McCluggage, W. Glenn;
- Kaplan, Richard S.;
- Jayson, Gordon C.;
- Oza, Amit;
- Harkin, D. Paul;
- Herrington, C. Simon;
- Kennedy, Richard;
- Gourley, Charlie
Publication type:
journal article
Distinct implications of different BRCA mutations: efficacy of cytotoxic chemotherapy, PARP inhibition and clinical outcome in ovarian cancer.
Published in:
OncoTargets & Therapy, 2017, v. 10, p. 2539, doi. 10.2147/OTT.S102569
By:
- Hollis, Robert L.;
- Churchman, Michael;
- Gourley, Charlie
Publication type:
Article
Molecular stratification of endometrioid ovarian carcinoma predicts clinical outcome.
Published in:
Nature Communications, 2020, v. 11, n. 1, p. N.PAG, doi. 10.1038/s41467-020-18819-5
By:
- Hollis, Robert L.;
- Thomson, John P.;
- Stanley, Barbara;
- Churchman, Michael;
- Meynert, Alison M.;
- Rye, Tzyvia;
- Bartos, Clare;
- Iida, Yasushi;
- Croy, Ian;
- Mackean, Melanie;
- Nussey, Fiona;
- Okamoto, Aikou;
- Semple, Colin A.;
- Gourley, Charlie;
- Herrington, C. Simon
Publication type:
Article
Pharmacogenetics of Smoking Cessation in General Practice: Results From the Patch II and Patch in Practice Trials.
Published in:
Nicotine & Tobacco Research, 2011, v. 13, n. 3, p. 157, doi. 10.1093/ntr/ntq246
By:
- David, Sean P.;
- Johnstone, Elaine C.;
- Churchman, Michael;
- Aveyard, Paul;
- Murphy, Michael F.G.;
- Munafò, Marcus R.
Publication type:
Article
Analysis of variants in DNA damage signalling genes in bladder cancer.
Published in:
BMC Medical Genetics, 2008, v. 9, p. 1, doi. 10.1186/1471-2350-9-69
By:
- Choudhury, Ananya;
- Elliott, Faye;
- Iles, Mark M.;
- Churchman, Michael;
- Bristow, Robert G.;
- Bishop, D Timothy;
- Kiltie, Anne E.
Publication type:
Article

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