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- Title
A systems approach to traditional oriental medicine.
- Authors
Kim, Hyun Uk; Ryu, Jae Yong; Lee, Jong Ok; Lee, Sang Yup
- Abstract
The article analyzes the molecular and systems-level characteristics of traditional oriental medicines (TOMs), which are based on a multicomponent, multitarget approach. It proposes how structural similarities of TOM-derived compounds to human metabolites can facilitate the identification of their mechanisms of action and potentially reduce toxicities. It also proposes that such strategies can facilitate further integration of TOM into modern drug discovery and development.
- Subjects
TRADITIONAL medicine; ASIAN medicine; METABOLITES; TOXICITY testing; DRUG development
- Publication
Nature Biotechnology, 2015, Vol 33, Issue 3, p264
- ISSN
1087-0156
- Publication type
Article
- DOI
10.1038/nbt.3167