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- Title
Gross examination by the surgeon as an alternative to frozen section for assessment of adequacy of surgical margin in head and neck squamous cell carcinoma.
- Authors
Chaturvedi, Pankaj; Datta, Sourav; Nair, Sudhir; Nair, Deepa; Pawar, Prashant; Vaishampayan, Sagar; Patil, Asawari; Kane, Shubhada
- Abstract
Background The cost-effectiveness of the frozen section for assessment of margin in head and neck squamous cell carcinoma (HNSCC) is still contentious. The purpose of this study was to evaluate whether gross examination of margin is an alternative to frozen section. Methods It was a prospective observational study in 145 consecutive patients undergoing surgery for HNSCC. Surgical margins were first assessed by the surgeons with a metallic scale. All specimens were then examined using frozen section and permanent section. Results Overall, 83% of inadequate margins were detected by frozen section. The chances of inadequate margin were very low if gross surgical margin were 7 mm or more. Gross examination alone (with 7 mm as cutoff) predicted 88% of the inadequate surgical margin. There was no difference in precision of frozen section vis-à-vis gross examination with 7 mm cut off ( p ≤ .8). Conclusion Achievement of 7 mm surgical margin measured by a surgeon obviates the need for frozen section. © 2013 Wiley Periodicals, Inc. Head Neck 36: 557-563, 2014
- Subjects
CRYOBIOLOGY; SQUAMOUS cell carcinoma; CANCER patients; SURGICAL site; BIOLOGY
- Publication
Head & Neck, 2014, Vol 36, Issue 4, p557
- ISSN
1043-3074
- Publication type
Article
- DOI
10.1002/hed.23313