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- Title
Serum Uric Acid to Albumin Ratio Can Predict Contrast-Induced Nephropathy in ST-Elevation Myocardial Infarction Patients Undergoing Primary Percutaneous Coronary Intervention.
- Authors
Şaylık, Faysal; Çınar, Tufan; Akbulut, Tayyar; Selçuk, Murat
- Abstract
Contrast-induced nephropathy (CIN) is one of the common complication of ST-elevation myocardial infarction (STEMI) following primary percutaneous coronary intervention (pPCI). Serum uric acid to albumin ratio (UAR) is a novel marker, which is associated with acute kidney injury in intensive care unit patients. We investigated the predictive value of UAR for the development of CIN in STEMI patients (n = 1379) after pPCI. The diagnosis of CIN was made based on an increase of basal creatinine levels >.5 mg/dL or 25% within 72 h after pPCI; 128 patients were in the CIN (+) group and 1251 patients were in the CIN (−) group. CIN (+) patients had higher serum uric acid (SUA), UAR, and lower albumin levels than CIN (−) patients. Age, diabetes, hypertension, hemoglobin, glucose at admission, basal creatinine, peak troponin I, total bilirubin, contrast volume/glomerular filtration rate, and UAR were independent predictors of CIN. A cutoff value of 1.62 for UAR detected CIN development with a sensitivity of 54% and specificity of 87.4%, and the discrimination ability of UAR was better than that of SUA or albumin. In conclusion, UAR was an independent predictor of the development of CIN.
- Subjects
KIDNEY disease diagnosis; ALBUMINS; INTENSIVE care units; TROPONIN; GLOMERULAR filtration rate; HYPERTENSION; PERCUTANEOUS coronary intervention; PREDICTIVE tests; HEMOGLOBINS; CONTRAST media; DIABETES; KIDNEY diseases; ST elevation myocardial infarction; CORONARY angiography; DESCRIPTIVE statistics; URIC acid; SENSITIVITY &; specificity (Statistics); DATA analysis software; ACUTE kidney failure; CREATININE
- Publication
Angiology, 2023, Vol 74, Issue 1, p70
- ISSN
0003-3197
- Publication type
Article
- DOI
10.1177/00033197221091605