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- Title
Longitudinal study of the socioeconomic burden of Parkinson’s disease in Germany.
- Authors
Winter, Y.; Balzer-Geldsetzer, M.; Spottke, A.; Reese, J. P.; Baum, E.; Klotsche, J.; Rieke, J.; Simonow, A.; Eggert, K.; Oertel, W. H.; Dodel, Richard
- Abstract
Objective: To determine the health economic burden on patients with Parkinson’s disease (PD) in Germany over a 12-month observation period and provide a comprehensive analysis of cost-driving factors. Methods and patients: Patients with PD ( n = 145) were recruited from two clinical departments, two office-based neurologists and 12 GPs. Clinical evaluations were performed at baseline, 3, 6 and 12 months. Disease severity was measured using the Unified Parkinson’s Disease Rating Scale (UPDRS). Cost data were assessed based on a patient diary and via personal structured interviews at the respective time-points. Costs were calculated from the societal perspective (2009 €). Cost-driving factors were identified by multivariate regression analysis. Results: Mean annual costs totalled €20 095 per patient. Amongst direct costs, the highest expenditures (€13 158) were for drugs (€3526) and inpatient care including nursing homes (€3789). Indirect costs accounted for 34.5% (€6937) of total costs. Costs of home care provided by family accounted for 20% of direct costs. Cost-driving factors were identified for total costs (UPDRS, fluctuations, dyskinesia and younger age), direct costs (UPDRS, fluctuations), patient expenditures (UPDRS, depression) and drug costs (younger age). Conclusion: Parkinson’s disease has a chronic course with growing disability and considerable socioeconomic burden. Disease progression leads to an increasing number of patients who require costly institutionalized care. Home care is a major factor influencing patients’ families. Healthcare programmes aimed at reducing the burden of PD on society and individuals should consider cost-driving factors of PD.
- Subjects
GERMANY; MEDICAL economics; PARKINSON'S disease; REGRESSION analysis; MEDICAL care
- Publication
European Journal of Neurology, 2010, Vol 17, Issue 9, p1156
- ISSN
1351-5101
- Publication type
Article
- DOI
10.1111/j.1468-1331.2010.02984.x